Phylogenetic inference: how much evolutionary history is knowable?
نویسندگان
چکیده
منابع مشابه
Phylogenetic inference: how much evolutionary history is knowable?
In order to reconstruct phylogenetic trees from extremely dissimilar sequences it is necessary to estimate accurately the extent of sequence divergence. In this paper a new method of sequence analysis, Markov triple analysis, is developed for determining the relative frequencies of nucleotide substitutions within the three branches of a three-taxon dendrogram. Assuming that nucleotide sites are...
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Severe sepsis and septic shock are major problems as the result of high rates morbidity andmortality in intensive care units (ICUs). In the presence of septic shock, each hour of delay inthe administration of effective antibiotics is associated with a measurable increase in mortality.Aminoglycosides are effective broad-spectrum antibiotics that are commonly used in ICUs forthe treatment of life...
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Phylogenetic profiling is a well-established approach for predicting gene function based on patterns of gene presence and absence across species. Much of the recent developments have focused on methodological improvements, but relatively little is known about the effect of input data size on the quality of predictions. In this work, we ask: how many genomes and functional annotations need to be...
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An investigation of the effect of the number of choice sets, starting point and the choice of bid vectors in choice experiments
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 1997
ISSN: 0737-4038,1537-1719
DOI: 10.1093/oxfordjournals.molbev.a025757